Peyronie’s Disease: Causes, Symptoms, & Treatments

Men are often reluctant to discuss their sexual health out of embarrassment, fear of judgement, or simply because they don’t understand what’s happening. Ignoring these issues, however, can have long-term consequences like erectile dysfunction, emotional distress and anxiety, and can even cause irreparable damage to intimate relationships. Which is why it is understandable that experts believe that roughly 9 percent of men suffer from some form of Peyronie’s disease.

What is Peyronie’s Disease?

Peyronie’s disease is characterized by a fibrous scar tissue that forms beneath the surface of the penis that can alter its appearance and function. If left untreated, this scar tissue, which can be mild or acute, can make it problematic for otherwise healthy men to have normal erections by creating a painful curvature of the penis which can make having sex difficult or impossible. Although the symptoms can sometimes relieve themselves, often a male who is given this diagnosis should speak with their doctor to determine what options may be available to him to have it treated.

Although penises, like fingerprints, are all different and can even have a natural curve to them, men who experience pain when erect or during sex should speak to their doctor about the possibility that these problems stem from Peyronie’s disease.

Signs & Symptoms

The symptoms that men with Peyronie’s disease may notice can develop quickly or slowly over time. Regardless of the speed at which Peyronie’s disease symptoms develop, the most common include:

· Scar Tissue Build-Up: A man may notice hard lumps or bands of tissue under the skin of his penis.
· Significant Penis Bend: A major symptom of Peyronie’s is penile curvature in any direction, defined by an unnatural and severe curve or bend, with or without an erection.
· Misshapen Penis: Occasionally, this disease can cause portions of the erect penis to narrow, often resembling an hourglass in shape.
· Penis Shortening: Some men note that the length of their penis is reduced when Peyronie’s is present.
· Penis Pain: Peyronie’s can cause a man to experience penile pain whether he has an erection or not.
· Erectile Dysfunction: Otherwise healthy men with Peyronie’s may experience problems getting or maintaining an erection.

What Causes Peyronie’s Disease?

Unfortunately, the exact Peyronie’s disease cause is still unknown , however, it frequently accompanies physical trauma. When a normal penis becomes aroused, blood rushes in and fills its chambers causing it to become erect. The elastic tissue alongside these chambers acts as a protective sheath and allows for a full erection. When the sheath becomes damaged due to trauma, hard scar tissue called plaque – essentially a buildup of collagen – forms and causes inelasticity. Without the required flexibility, the penis creates a curvature, or bend. Generally, Peyronie’s disease causes are brought about by things like:

· Acute Injury:
If a man hits his penis very hard, or bends it because of an accident, it can cause an acute injury. Likewise, vigorous sexual activity, and bending of the penis during penetration, or by his partner’s pubic bone, are also common causes. He may or may not realize he’s hurt himself immediately as the pain can diminish quickly.

· Chronic & Repeated Injury:
Certain athletic activities, such as bicycling or horseback riding for long periods, can cause repeated injury to a man’s penis. Since they involve a great deal of sitting, pressure, and jolts to the groin area, that can cause Peyronie’s to develop over time. As with any acute injury, the man may not realize the damage until symptoms appear.

· Prostate Surgery:
In recent years, a growing trend regarding Peyronie’s has been noted for those suffering from prostate cancer. Many urologists now suspect that, at least in some men who have undergone radical prostatectomy, there is reason to believe that complications from this type of surgery can induce Peyronie’s as the patient recovers from the procedure.

· Autoimmune Disorders:
Autoimmune Disorders: Some experts believe that autoimmune diseases that affect connective tissues may lead to Peyronie’s disease. If the immune system attacks cells inside the penis, it can lead to inflammation, scarring, and severe curvature.

· Family History:
Men who have close relatives with Peyronie’s disease may also be at risk for developing it themselves. Although an uncomfortable topic to bring up, understanding your family’s health and history can help both you and your doctor manage the disease more easily.

· Age:
Sexual performance naturally declines as a man ages with changes in hormonal levels and elasticity of penile tissue. The inclination towards Peyronie’s also increases, affecting men who are over the age of 55, more often than their younger counterparts. If he smokes, consumes alcohol, ingests certain drugs, has had prostate surgery, or other health issues are present, a man’s risk is even greater as he ages.

Peyronie’s Disease Treatment Options

· Poor dental health
A recent study published in the Journal of Sexual Medicine reported that men with severe periodontal disease were three times more likely to have consistent difficulties having an erection. While this may be a case of correlation rather than causation, poor dental health has long been associated with vascular disease, which is known to contribute to ED.

Peyronie’s disease

If you are experiencing pain or have noticed a curvature of your penis, it is important to seek care from a healthcare provider, especially if it prevents you from having intercourse or impairs your ability to maintain healthy, intimate relationships. Your healthcare provider will begin by reviewing your medical and family history in addition to a physical exam in which he or she will examine your penis for signs of plaque. If a physical exam fails to produce evidence of plaque, or your healthcare provider would like to pinpoint the exact location of the plaque buildup, imaging tests such as an X-ray or ultrasound may be required. Common recommendations for Peyronie’s disease treatments could include:

· A Wait-and-see Approach:
In some instances, Peyronie’s disease clears up on its own, though often some sort of treatment – at least some sort of pain relief, in the short term – is necessary. If there aren’t pronounced symptoms or discomfort, a doctor may decide to first wait before doing anything else.

· Making Lifestyle Changes:
Some studies suggest that Peyronie’s disease could be made worse if men have certain habits, including smoking, drug use, and alcohol consumption. Cutting back on these things or eliminating them entirely – along with exercising more and eating right – could not only return you to better health overall, it may also help with the condition.

Prescription Drug Treatment:
Medication focuses on reducing plaque to curtail overall pain and discomfort thereby improving the men’s health. While very expensive, collagenase is the only FDA-approved medicine for Peyronie’s disease and is injected into the scar tissue to help break it down. While clinical trials prove that these injections can help to reduce the curve, this treatment of Peyronie’s can cause significant side effects including penile fractures, allergic reactions, bleeding, swelling, itching, erection problems, and painful sex.

One of the most popular prescription medicines for treating Peyronie’s is Verapimil, which is typically prescribed for treating high blood pressure and angina. This medicine was originally intended to be used to prevent strokes, heart attacks and various kidney problems, but was also shown to have some benefit for men suffering from Peyronie’s disease. Within the body, Verapimil works by relaxing the blood vessels throughout the body to improve the overall flow of blood. Unfortunately, as with many other such prescription medicines, it can have adverse side effects for some users including hypotension, increased liver enzyme production, and a host of nuisance conditions like frequent constipation, dizziness, headaches, indigestion, nausea, rashes, edema, and even swollen gums.

Another popular prescription option is Xiaflex. Originally designed to treat Dupuytren’s Contracture, this medicine works by dissolving some of the plaque deposits that can build up in the extremities. Although this medicine has been proven to be effective at reducing the symptoms in some patients, many of the side effects are enough to give some men pause when considering it as a treatment for Peyronie’s. Some of the known side effects include corporal rupture, tendon and ligament damage, nerve damage, and it can even elevate the risk of excessive bleeding.

· Exercises to Treat Peyronie’s:
For some, the distressing symptoms of Peyronie’s disease can be mitigated with exercise of the affected area. Often prescribed to patients as the first step or in tandem with injectable treatments such as Xiaflex, this program can often be a painful endeavor as it requires forceful manipulation of the penis. For those who choose exercise to lessen the effects of Peyronie’s, it often becomes a tedious affair requiring a fairly strict regimen of exercises lasting five to six weeks after the injection. As this treatment protocol typically consists of eight treatments administered every five to six weeks, the entire process can take up to a year to complete.

· Surgery:
Surgery is recommended only in long-term Peyronie’s disease cases in which the curvature of the penis is acute and has been unresponsive to non-invasive treatments. The most common surgeries include a penile implant to help sustain an erection and straighten the penis, grafting to cover openings in the tunica albuginea once scar tissue is removed, and plication in which a surgeon pinches or removes a piece of tunica albuginea on the opposite side of the plaque to help straighten the penis. These surgeries have risks including shortening, numbness, or you could lose your erectile function entirely.

· Vacuum Devices:
These devices attempt to stretch and bend the penis to regain a normal shape through mechanical traction. It requires daily use, over the course of several months, through the use of an at-home, inflatable vacuum cylinder. While they can provide small improvements to penis curvature, they are unable to provide significant improvements in men with moderate to severe penis curvature, and men who experience erectile dysfunction in addition to Peyronie’s disease.

A Natural Solution with GAINSWave®

Fortunately, if you’re searching for a more natural, non-invasive treatment for Peyronie’s disease, GAINSWave can help. Peyronie’s disease is treatable, and most men are able to return to optimal sexual performance after therapy.

This treatment uses a premium brand of high frequency low-intensity shockwaves, or soundwaves, to break down scar tissue (plaque) and open blood vessels and create new ones. This increases blood flow, reduces the curvature of the penis, and corrects any potential erectile dysfunction.

GAINSWave is one of the only drug-free, surgery-free therapeutic options for men with Peyronie’s disease that has proven its effectiveness in clinical trials.



“The use of LI-ESWT in [Peyronie’s disease] has been reported since the late 1980s” and recent research published in Translational Andrology and Urology found that this type of treatment can help reduce both curvature and pain. The authors concluded that “LI-ESWT remains a useful and valid minimally invasive treatment option for men with PD who have failed with conventional medical therapy and are not keen to undergo surgical intervention.”



For more information on overcoming Peyronie’s disease, watch our Medical Moment webinar featuring Urologist, Dr. Brandeis.

Today, thousands of patients have benefited from GAINSWave therapy. Contact us to make an appointment.

Tennessee Center for Regenerative Medicine Privacy Policy

Last Updated on November 29, 2016. This privacy policy is effective immediately.

Introduction

At Tennessee Center for Regenerative Medicine (the “Company” or “We”), we respect your privacy and are committed to protecting it through our compliance with this policy.

This policy describes the types of information we may collect from you or that you may provide when you visit this website (our “Website”) and our practices for collecting, using, maintaining, protecting and disclosing that information.

This policy applies to information we collect:

  • On this Website.
  • In e-mail, text and other electronic messages between you and this Website.
  • Through mobile and desktop applications you download from this Website, which provide dedicated non-browser-based interaction between you and this Website.
  • When you interact with our advertising and applications on third-party websites and services, if those applications or advertising include links to this policy.

It does not apply to information collected by:

  • us offline or through any other means, including on any other website operated by Company or any third party (including our affiliates and subsidiaries); or
  • any third party (including our affiliates and subsidiaries), including through any application or content (including advertising) that may link to or be accessible from or on the Website.

Please read this policy carefully to understand our policies and practices regarding your information and how we will treat it. If you do not agree with our policies and practices, your choice is not to use our Website. By accessing or using this Website, you agree to this privacy policy. This policy may change from time to time. Your continued use of this Website after we make changes is deemed to be acceptance of those changes, so please check the policy periodically for updates.

Children Under the Age of 13

Our Website is not intended for children under 13 years of age. No one under age 13 may provide any personal information to or on the Website. We do not knowingly collect personal information from children under 13. If you are under 13, do not use or provide any information on this Website or on or through any of its features/register on the Website, make any purchases through the Website, use any of the interactive or public comment features of this Website or provide any information about yourself to us, including your name, address, telephone number, e-mail address or any screen name or user name you may use. If we learn we have collected or received personal information from a child under 13 without verification of parental consent, we will delete that information. If you believe we might have any information from or about a child under 13, please contact us via our contact us link.

Information We Collect About You and How We Collect It

We collect several types of information from and about users of our Website, including information:

  • by which you may be personally identified, such as name, postal address, e-mail address, telephone number or ANY OTHER INFORMATION THE WEBSITE COLLECTS THAT IS DEFINED AS PERSONAL OR PERSONALLY IDENTIFIABLE INFORMATION UNDER AN APPLICABLE LAW (“personal information”);
  • that is about you but individually does not identify you, and/or
  • about your internet connection, the equipment you use to access our Website and usage details.

We collect this information:

  • Directly from you when you provide it to us.
  • Automatically as you navigate through the site. Information collected automatically may include usage details, IP addresses and information collected through cookies, web beacons and other tracking technologies.
  • From third parties, for example, our business partners.

Information You Provide to Us.

The information we collect on or through our Website may include:

  • Information that you provide by filling in forms on our Website. This includes information provided at the time of registering to use our Website, subscribing to our service, posting material or requesting further services. We may also ask you for information when you report a problem with our Website.
  • Records and copies of your correspondence (including e-mail addresses), if you contact us.
  • Your responses to surveys that we might ask you to complete for research purposes.
  • Details of transactions you carry out through our Website and of the fulfillment of your orders. You may be required to provide financial information before placing an order through our Website.
  • Your search queries on the Website.

You also may provide information to be published or displayed (hereinafter, “posted”) on public areas of the Website, or transmitted to other users of the Website or third parties (collectively, “User Contributions”). Your User Contributions are posted on and transmitted to others at your own risk. Although we limit access to certain pages/you may set certain privacy settings for such information by logging into your account profile, please be aware that no security measures are perfect or impenetrable. Additionally, we cannot control the actions of other users of the Website with whom you may choose to share your User Contributions. Therefore, we cannot and do not guarantee that your User Contributions will not be viewed by unauthorized persons.

Information We Collect Through Automatic Data Collection Technologies.

As you navigate through and interact with our Website, we may use automatic data collection technologies to collect certain information about your equipment, browsing actions and patterns, including:

  • Details of your visits to our Website, including traffic data, location data, and other communication data and the resources that you access and use on the Website.
  • Information about your computer and internet connection, including your IP address, operating system and browser type.

We also may use these technologies to collect information about your online activities over time and across third-party websites or other online services (behavioral tracking). The information we collect automatically is statistical data and does not include personal information, but we may maintain it or associate it with personal information we collect in other ways or receive from third parties. It helps us to improve our Website and to deliver a better and more personalized service, including by enabling us to:

  • Estimate our audience size and usage patterns.
  • Store information about your preferences, allowing us to customize our Website according to your individual interests.
  • Speed up your searches.
  • Recognize you when you return to our Website.

The technologies we use for this automatic data collection may include:

  • Cookies (or browser cookies). A cookie is a small file placed on the hard drive of your computer. You may refuse to accept browser cookies by activating the appropriate setting on your browser. However, if you select this setting you may be unable to access certain parts of our Website. Unless you have adjusted your browser setting so that it will refuse cookies, our system will issue cookies when you direct your browser to our Website.
  • Flash Cookies. Certain features of our Website may use local stored objects (or Flash cookies) to collect and store information about your preferences and navigation to, from and on our Website. Flash cookies are not managed by the same browser settings as are used for browser cookies.
  • Web Beacons. Pages of our the Website may contain small electronic files known as web beacons (also referred to as clear gifs. pixel tags and single-pixel gifs) that permit the Company, for example, to count users who have visited those pages or opened an e-mail and for other related website statistics (for example, recording the popularity of certain website content and verifying system and server integrity).

We do not collect personal Information automatically, but we may tie this information to personal information about you that we collect from other sources or you provide to us.

Third-party Use of Cookies and Other Tracking Technologies.

Some content or applications, including advertisements, on the Website are served by third-parties, including advertisers, ad networks and servers, content providers and application providers. These third parties may use cookies alone or in conjunction with web beacons or other tracking technologies to collect information about you when you use our website. The information they collect may be associated with your personal information or they may collect information, including personal information, about your online activities over time and across different websites and other online services. They may use this information to provide you with interest-based (behavioral) advertising or other targeted content.

We do not control these third parties’ tracking technologies or how they may be used. If you have any questions about an advertisement or other targeted content, you should contact the responsible provider directly.

How We Use Your Information

We use information that we collect about you or that you provide to us, including any personal information:

  • To present our Website and its contents to you.
  • To provide you with information, products or services that you request from us.
  • To provide you with information about our services
  • To provide you with notices about your account/subscription, including expiration and renewal notices.
  • To carry out our obligations and enforce our rights arising from any contracts entered into between you and us, including for billing and collection.
  • To notify you about changes to our Website or any products or services we offer or provide though it.
  • To allow you to participate in interactive features on our Website.
  • In any other way we may describe when you provide the information.
  • To fulfill any purpose for which you provide it.
  • For any other purpose with your consent.

We may use the information we have collected from you to enable us to display advertisements to our advertisers’ target audiences. Even though we do not disclose your personal information for these purposes without your consent, if you click on or otherwise interact with an advertisement, the advertiser may assume that you meet its target criteria.

Disclosure of Your Information

We may disclose aggregated information about our users, and information that does not identify any individual, without restriction.

We may disclose personal information that we collect or you provide as described in this privacy policy:

  • To our subsidiaries and affiliates.
  • To contractors, service providers and other third parties we use to support our business and who are bound by contractual obligations to keep personal information confidential and use it only for the purposes for which we disclose it to them.
  • To a buyer or other successor in the event of a merger, divestiture, restructuring, reorganization, dissolution or other sale or transfer of some or all of the Company’s assets, whether as a going concern or as part of bankruptcy, liquidation or similar proceeding, in which personal information held by the Company about our Website users is among the assets transferred.
  • To third parties to market their products or services to you if you have consented to these disclosures. We contractually require these third parties to keep personal information confidential and use it only for the purposes for which we disclose it to them.
  • To fulfill the purpose for which you provide it. For example, if you give us an e-mail address to use the “e-mail a friend” feature of our Website, we will transmit the contents of that e-mail and your e-mail address to the recipients.
  • For any other purpose disclosed by us when you provide the information.
  • With your consent.

We may also disclose your personal information:

  • To comply with any court order, law or legal process, including to respond to any government or regulatory request.
  • To enforce or apply our terms of use and other agreements, including for billing and collection purposes.
  • If we believe disclosure is necessary or appropriate to protect the rights, property, or safety of the Company, our customers or others. This includes exchanging information with other companies and organizations for the purposes of fraud protection and credit risk reduction.

Choices About How We Use and Disclose Your Information

We strive to provide you with choices regarding the personal information you provide to us. We have created mechanisms to provide you with the following control over your information:

  • Tracking Technologies and Advertising. You can set your browser to refuse all or some browser cookies, or to alert you when cookies are being sent. To learn how you can manage your Flash cookie settings, visit the Flash player settings page on Adobe’s website. If you disable or refuse cookies, please note that some parts of this site may then be inaccessible or not function properly.
  • We do not control third parties’ collection or use of your information to serve interest-based advertising. However these third parties may provide you with ways to choose not to have your information collected or used in this way. You can opt out of receiving targeted ads from members of the Network Advertising Initiative (“NAI”) on the NAI’s website.

Accessing and Correcting Your Information

You may send us an e-mail via our contact link to request access to, correct or delete any personal information that you have provided to us. We cannot delete your personal information except by also deleting your user account. We may not accommodate a request to change information if we believe the change would violate any law or legal requirement or cause the information to be incorrect.

If you delete your User Contributions from the Website, copies of your User Contributions may remain viewable in cached and archived pages, or might have been copied or stored by other Website users. Proper access and use of information provided on the Website, including User Contributions, is governed by our terms of use.

Your California Privacy Rights

California Civil Code Section § 1798.83 permits users of our Website that are California residents to request certain information regarding our disclosure of personal information to third parties for their direct marketing purposes. To make such a request, please contact us via the Contact Us link.

Data Security

We have implemented measures designed to secure your personal information from accidental loss and from unauthorized access, use, alteration and disclosure

The safety and security of your information also depends on you. Where we have given you (or where you have chosen) a password for access to certain parts of our Website, you are responsible for keeping this password confidential. We ask you not to share your password with anyone.

Unfortunately, the transmission of information via the internet is not completely secure. Although we do our best to protect your personal information, we cannot guarantee the security of your personal information transmitted to our Website. Any transmission of personal information is at your own risk. We are not responsible for circumvention of any privacy settings or security measures contained on the Website.

Changes to Our Privacy Policy

It is our policy to post any changes we make to our privacy policy on this page. If we make material changes to how we treat our users’ personal information, we will notify you by e-mail to the e-mail address specified in your account and/or through a notice on the Website home page. The date the privacy policy was last revised is identified at the top of the page. You are responsible for ensuring we have an up-to-date active and deliverable e-mail address for you, and for periodically visiting our Website and this privacy policy to check for any changes.

Contact Information

To ask questions or comment about this privacy policy and our privacy practices, contact via our Contact Us link.

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